Abstract
35 patients with vitamin D deficiency rickets were investigated. PTH levels were determined by radio-immunoassay.
Serum phosphate is decreased. Serum calcium is related to age. Past 15 months of life, hypocalcemia is never observed. PTH has a tendency to decrease with age. No significant correlation could be found between calcium and PTH levels, nor between phosphate and PTH levels. The correlation between PTH levels and aminoaciduria is poor. The subjects were divided into three groups according to calcemia and age: group I-hypocalcemic children younger than 15 months; group II- normocalcemic children younger than 15 months; group III-normocalcemic children older than 15 months. PTH levels are always high in group I and variable in groups II, III.
The parathyroid function and parathyroid responsiveness to serum calcium, in vitamin D deficiency state are discussed according to these results.
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Vainsel, M., Manderlier, T. & Corvilain, J. STUDY OF PARATHYROID ACTIVITY IN VITAMIN D DEFICIENCY RICKETS. Pediatr Res 8, 128 (1974). https://doi.org/10.1203/00006450-197402000-00013
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DOI: https://doi.org/10.1203/00006450-197402000-00013
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