Abstract
New high sensitivity apparatus and particularly the discovery of pure gamma-emitting, low energy, short half-life radioisotopes have brought the use of radioisotope techniques, especially scintiscanning, within the orbit of paediatric diagnosis. Here, a series of color scintiscans is presented, the children in question having been admitted for suspected cerebral, renal, and hepatic ncoplasias. Tc99m was used for the cerebral scans, colloidal Tc90m sulfide for the hepatic, and Chlormerodrin Hg107 for the renal. The cerebral scintiscanning was performed on 25 children with suspected intracranial neoplasia. Seventy-six per cent of all cerebral tumours encountered were correctly localized. Within this percentage, the success rate with supratentorial tumors was 100% and with subtentorial 61.5%. Renal scintiscanning proves to be of particular value in the diagnosis of primary and metastatic tumors. While urography is an important tool for evaluating the morphology of the excretory cavities of the kidney, scintiscanning studies parenchyma conditions. Using colloidal TC99m which is localized by choice in the hepatosplenic reticuloendothelium, it is possible to detect the presence of primary hepatic tumors or metastases, if any. Findings showed that: (1) there are no particular contraindications to the use of scanning becuase the technique is free from toxicity, harmless, painless, and casy to use; (2) in pediatric age and, above all, in the early months of life, scanning makes it possible to solve diagnostic problems which in its absence would require much more laborious, traumatizing techniques: (3) with scanning, the effects of antiblastic therapy may be followed up over a period of time.
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Mussa, G., Mauri, M. & Bacolla, D. 48. Value of color scintiscanning in the diagnosis of cerebral, renal, and hepatic neoplasias in pediatrics. Pediatr Res 5, 93 (1971). https://doi.org/10.1203/00006450-197102000-00053
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DOI: https://doi.org/10.1203/00006450-197102000-00053