Abstract
The changes in serum β-liprptotein and the relative distribution of lipoproteins as well as the pattern of fatty acids have been followed in infants during the neonatal period. The data obtained were correlated to the intake as well as to the growth of the child. In infants living on human milk, the total content of β-lipoprotein increased from around 30% of the concentration in the mother's serum at birth, to around 80% in the 2nd week of life. During the same period the lipoptotein pattern changed from a predominance of the pre-β-lipoprotein band to a pattern with the β-lipoprotein as a dominating fraction with contribution from other lipoprotein fractions seen in normal adult sera as elucidated by means agar electrophoresis.
During the same period the fatty acid pattern also changed. At birth low values of oleic acid and linoleic acid and high values of palmitic acie and arachidonic acids were found in cord serum as compared to the corresponding values in the mothers' blood. During the 1st week the content of palmitic and arachidonic acids decreased slightly, whereas the oleic acid was found to increase.
Somewhat different values were found in infants of low birth weight, where the linolic acid was found to be very low.
Related changes in serum levels of viramin E will be discussed.
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Clausen, J., Friis-Hansen, B. 14. Changes in the lipid pattern of human sera in the neonatal period. Pediatr Res 5, 85–86 (1971). https://doi.org/10.1203/00006450-197102000-00019
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DOI: https://doi.org/10.1203/00006450-197102000-00019