Abstract
The formation of the β-structure of well-fractionated low molecular weight samples of poly(S-carboxymethyl-L-cysteine) was examined. In solutions with no added salt and a polymer concentration of 1×10−3 residue mol dm−3 (N), the β-structure was formed at a pH lower than about 3.5 for one sample (DPn=15.6), while it was not formed throughout the entire soluble range of pH for another sample (DP≃12). The concentration dependent β-disordered conversion of a sample (DPn=15.6) was not reversible. In 20 mM NaClO4 solutions, two samples, DP≃10 and DPn=15.6, remained essentially in a disordered state throughout the entire soluble range of pH when examined at a polymer concentration of 1×10−3N. The chain length dependent formation of the β-structure was compared with available data on oligo(L-glutamic acid) [M. Rinaudo and A. Domard, J. Am. Chem. Soc., 98, 6360 (1975)]. An uncharged β-structure consisting of S-car-boxymethyl-L-cysteine was found to be less stable than that of L-glutamic acid residue, relative to the disordered states of the respective residues.
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Maeda, H., Iwase, T. & Ikeda, S. The Effect of Chain Length on the Formation of the Intermolecular β-Structure of Poly(S-carboxy-methyl-L-cysteine). Polym J 16, 471–477 (1984). https://doi.org/10.1295/polymj.16.471
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DOI: https://doi.org/10.1295/polymj.16.471