Gene expression is a highly interconnected multistep process. A recent meeting in Iguazu Falls, Argentina, highlighted the need to uncover both the molecular details of each single step as well as the mechanisms of coordination among processes in order to fully understand the expression of genes.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Maniatis, T. & Reed, R. Nature 416, 499–506 (2002).
Espinosa, J.M., Verdun, R.E. & Emerson, B.M. Mol. Cell 12, 1015–1027 (2003).
Ladurner, A.G., Inouye, C., Jain, R. & Tjian, R. Mol. Cell 11, 365–376 (2003).
Lusic, M., Marcello, A., Cereseto, A. & Giacca, M. EMBO J. 22, 6550–6561 (2003).
Cartegni, L. & Krainer, A.R. Nat. Genet. 30, 377–384 (2002).
Pagani, F. et al. Hum. Mol. Genet. 12, 1111–1120 (2003).
Baralle, M. et al. J. Med. Genet. 40, 220–222 (2003).
de la Mata, M. et al. Mol. Cell 12, 525–532 (2003).
Morillon, A., O'Sullivan, J., Azad, A., Proudfoot, N. & Mellor, J. Science 300, 492–495 (2003).
Alen, C. et al. Mol. Cell 10, 1441–1452 (2002).
Papa, F.R., Zhang, C., Shokat, K. & Walter, P. Science 302, 1533–1537 (2003).
Wollerton, M.C., Gooding, C., Wagner, E.J., Garcia-Blanco, M.A. & Smith, C.W. Mol. Cell 13, 91–100 (2004).
Lewis, B.P., Green, R.E. & Brenner, S.E. Proc. Natl. Acad. Sci. USA 100, 189–192 (2003).
Ishigaki, Y., Li, X., Serin, G. & Maquat, L.E. Cell 106, 607–617 (2001).
Lejeune, F., Li, X. & Maquat, L.E. Mol. Cell 12, 675–687 (2003).
Huang, Y., Gattoni, R., Stevenin, J. & Steitz, J.A. Mol. Cell 11, 837–843 (2003).
Hirose, T., Shu, M.D. & Steitz, J.A. Mol. Cell 12, 113–123 (2003).
Nguyen, V.T., Kiss, T., Michels, A.A. & Bensaude, O. Nature 414, 322–325 (2001).
Kwek, K.Y. et al. Nat. Struct. Biol. 9, 800–805 (2002).
Lund, E., Guttinger, S., Calado, A., Dahlberg, J.E. & Kutay, U. Science 303, 95–98 (2004).
Marcello, A. et al. EMBO J. 22, 2156–2166 (2003).
Acknowledgements
I thank D. Bentley for refreshing my memory and for constructive comments on the manuscript. T.M. is a fellow of the Keith R. Porter Endowment for Cell Biology.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Misteli, T. The flow of gene expression. Nat Struct Mol Biol 11, 202–205 (2004). https://doi.org/10.1038/nsmb0304-202
Issue Date:
DOI: https://doi.org/10.1038/nsmb0304-202