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Structure of the carboxy-terminal domain of bovine rhodopsin

Nature Structural Biology volume 2, pages 832–834 (1995)Cite this article

The biologically active carboxy-terminal peptide of the G-protein receptor, rhodopsin, forms a compact structure, suggesting that it is a structural domain in this integral membrane protein. The disposition of serines explains receptor kinase specificity.

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References

  1. Albert, A.D. & Litman, B.J. Biochemistry 17, 3893–3900 (1978).

    Article  CAS  Google Scholar 

  2. Hargrave, P.A. et al. Biophys. struct. Mech. 9, 235–244 (1983).

    Article  CAS  Google Scholar 

  3. Schertler, G.F.X., Villa, C. & Henderson, R. Nature 362, 770–772 (1993).

    Article  CAS  Google Scholar 

  4. Ohguro, H., Johnson, R.S., H.Ericsson, L., Walsh, K.A. & Palczewski, K. Biochemistry 33, 1023–1028 (1994).

    Article  CAS  Google Scholar 

  5. Karnik, S.S., Ridge, K.D., Bhattacharya, S. & Khorana, H.G. Proc. natn. Acad. U.S.A. 40–44 (1993).

  6. Tajima, S., Enomoto, K. & Sato, R. Archs Biochem. Biophys. 172, 90–97 (1976).

    Article  CAS  Google Scholar 

  7. Takemoto, D.J., Morrison, D., Davis, L.C. & Takemoto, L.J. Biochem. J. 235, 309–312 (1986).

    Article  CAS  Google Scholar 

  8. Konig, B. et al. Proc. natn. Acad. Sci. U.S.A. 86, 6878–6882 (1989).

    Article  CAS  Google Scholar 

  9. Phillips, W.J. & Cerione, R.A. Biochem. J. 299(Pt 2), 351–357 (1994).

    Article  CAS  Google Scholar 

  10. Takemoto, D.J., Takemoto, L.J., Hansen, J. & Morrison, D. Biochem. J. 232, 669–672 (1985).

    Article  CAS  Google Scholar 

  11. Pistorius, A.M. & DeGrip, W.J. Biochem. biophys. Res. Commun. 198, 1040–1045 (1994).

    Article  CAS  Google Scholar 

  12. Hausdorf, W.P., Hnatowich, M., O'Dowd, B.F., Caron, M.G. & Lefkowitz, R.J. J. biol. Chem. 265, 1388–1393 (1990).

    Google Scholar 

  13. Palczewski, K., Arendt, A., McDowell, J.H. & Hargrave, P.A. Biochemistry 28, 8764–8770 (1989).

    Article  CAS  Google Scholar 

  14. Boesze-Battaglia, K. & Albert, A. J. biol. Chem. 265, 20727–20730 (1990).

    CAS  PubMed  Google Scholar 

  15. Liebman, P.A. & Evanczuk, A.T. Meth. Enzym. 81, 532–542 (1982).

    Article  CAS  Google Scholar 

  16. Miller, J.L., Fox, D.A. & Litman, B.J. Biochemistry 25, 4983–4988 (1986).

    Article  CAS  Google Scholar 

  17. Nagayama, K., Kumar, A., Wüthrich, K. & Ernst, R.R. J. magn. Reson. 40, 321–334 (1980).

    CAS  Google Scholar 

  18. Rance, M. et al. Biochem. biophys. Res. Commun. 117, 479–485 (1983).

    Article  CAS  Google Scholar 

  19. Braunschweiler, L. & Ernst, R.R. J. magn. Reson. 53, 521–528 (1983).

    CAS  Google Scholar 

  20. Bax, A. & Davis, D.G. J. magn. Reson. 65, 355–360 (1985).

    CAS  Google Scholar 

  21. Kumar, A., Ernst, R.R. & Wüthrich, K. Biochem. biophys. Res. Commun. 95, 1–6 (1980).

    Article  CAS  Google Scholar 

  22. Wishart, D.S., Sykes, B.D. & Richards, F.M. Biochemistry 31, 1647–1651 (1992).

    Article  CAS  Google Scholar 

  23. Wüthrich, K., Billeter, M. & Braun, W. J. molec. Bio. 169, 949–961 (1983).

    Article  Google Scholar 

  24. Güntert, P., Braunk, W. & Wüthrich, K. J. molec. Biol. 217, 517–530 (1991).

    Article  Google Scholar 

  25. Weiner, S.J. et al. J. Am. chem. Soc. 106, 765–784 (1984).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Biochemistry, University at Buffalo, Buffalo, New York, 14214, USA

    Philip L. Yeagle & Arlene D. Albert

  2. Department of Biophysics, Roswell Park Cancer Institute, Buffalo, New York, 14263, USA

    James L. Alderfer

Authors
  1. Philip L. Yeagle
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  2. James L. Alderfer
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  3. Arlene D. Albert
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Yeagle, P., Alderfer, J. & Albert, A. Structure of the carboxy-terminal domain of bovine rhodopsin. Nat Struct Mol Biol 2, 832–834 (1995). https://doi.org/10.1038/nsb1095-832

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