Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Correspondence
  • Published:

Structural modelling of a type I DNA methyltransferase

Amino-acid sequence comparison and tertiary structure modelling suggest a structure for type I DNA methyltransferases and an evolutionary link to type II DNA methyltransferases.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Wilson, G.G. & Murray, N.E. Annu. Rev. Genet. 25, 585–627 (1991).

    Article  CAS  Google Scholar 

  2. Barcus, V.A. & Murray, N.E. In Population genetics of bacteria in Society for General Microbiology Symposium 52 (eds. Baumberg, S., Young, J.P.W., Saunders, S.R. & Wellington, E.M.H.) 31–58 (Cambridge University Press, Cambridge; 1995).

    Google Scholar 

  3. Kelleher, J.E., Daniel, A.S. & Murray, N.E. J. molec. Biol. 221, 431–440 (1991).

    Article  CAS  Google Scholar 

  4. Cooper, L.P. & Dryden, D.T.F. J. molec. Biol. 236, 1011–1021 (1994).

    Article  CAS  Google Scholar 

  5. Wilson, G.G. Meth. Enzym. 216, 259–279 (1992).

    Article  CAS  Google Scholar 

  6. Kumar, S. et al. Nucleic Acids Res. 22, 1–10 (1994).

    Article  CAS  Google Scholar 

  7. Klimasauskas, S., Kumar, S., Roberts, R.J. & Cheng, X. Cell 76, 357–369 (1994).

    Article  CAS  Google Scholar 

  8. Labahn, J. et al. Proc. natn. Acad. Sci. U.S.A. 91, 10957–10961 (1994).

    Article  CAS  Google Scholar 

  9. Cheng, X. Annu. Rev. Biophys. Biomol. Struct. 24, 293–318 (1995).

    Article  CAS  Google Scholar 

  10. Schluckebier, G., O'Gara, M., Saenger, W. & Cheng, X. J. molec. Biol. 247, 16–20 (1995).

    Article  CAS  Google Scholar 

  11. Lauster, R. J. molec. Biol. 206, 313–321 (1989).

    Article  CAS  Google Scholar 

  12. Noyer-Weidner, M., Walter, J., Terschüren, P.-A., Chai, S. & Trautner, T.A. Nucleic Acids Res. 22, 4066–4072 (1994).

    Article  CAS  Google Scholar 

  13. Rost, B. & Sander, C. J. molec. Biol. 232, 584–599 (1993).

    Article  CAS  Google Scholar 

  14. Rossman, M.G., Liljas, A., Bränden, C.-I. & Banaszak, L.J. in The Enzymes, 3rd ed. vol XI. (ed.Boyer, P.D.) 61–102 (Academic Press ; 1975).

    Google Scholar 

  15. Willcock, D.F., Dryden, D.T.F. & Murray, N.E. EMBO J. 13, 3902–3908 (1994).

    Article  CAS  Google Scholar 

  16. Meister, J. et al. EMBO J. 12, 4585–4591 (1993).

    Article  CAS  Google Scholar 

  17. Taylor, I.A., Davis, K.G., Watts, D. & Kneale, G.G. EMBO J. 13, 5772–5778 (1994).

    Article  CAS  Google Scholar 

  18. Powell, L.M. & Murray, N.E. Nucleic Acids Res. 23, 967–974 (1995).

    Article  CAS  Google Scholar 

  19. Chen, A., Powell, L.M., Dryden, D.T.F., Murray, N.E. & Brown, T. Nucleic Acids Res. 23, 1177–1183 (1995).

    Article  CAS  Google Scholar 

  20. Powell, L.M., Dryden, D.T.F., Willcock, D.F., Pain, R.H. & Murray, N.E. J. Mol Biol. 234, 60–71 (1993).

    Article  CAS  Google Scholar 

  21. Burckhardt, J., Weisemann, J., Hamilton, D.L. & Yuan, R. J. molec. Biol. 153, 425–440 (1981).

    Article  CAS  Google Scholar 

  22. Dybvig, K. & Yu, H. Molec. Microbiol. 12, 547–560 (1994).

    Article  CAS  Google Scholar 

  23. Jones, T.A. J. appl. Crystallogr. 11, 268–272 (1978).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dryden, D., Sturrock, S. & Winter, M. Structural modelling of a type I DNA methyltransferase. Nat Struct Mol Biol 2, 632–635 (1995). https://doi.org/10.1038/nsb0895-632

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nsb0895-632

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing