New results indicate that a K+ channel switches from a closed state to an open state by widening the hydrophobic pore on the cytoplasmic side of the membrane.
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References
Perozo, E., Cortes, D.M. & Cuello, L.G. Nature Struct. Biol. 5, 459–469 (1998).
Doyle, D.A. et al. Science 280, 69–76 (1998).
Cuello, L.G. et al. Biochemistry 37, 3229–3236 (1998).
Ogawa, S.&., McConnell, H.M. Proc. Natl. Acad. Sci. USA 58, 19–26 (1967).
Todd, A.P. et al. Proteins Struct. Funct. Genet. 6, 294–305 (1989).
Armstrong, C.M. et al. J. Gen. Physiol. 80, 663–682 (1982).
Farrens, D.L. et al. Science 274, 768–770 (1996).
Subramanian, S., Gerstein, M., Oesthelt, D. & Henderson, R. EMBO J. 12, 1–8 (1993).
Unwin, N. Nature 373, 37–43 (1995).
Rabenstein, M.D. & Shin, Y.-K. Proc. Natl. Acad. Sci. USA 92, 8239–8243 (1995).
Ottemann, K.M. et al. Biochemistry 37, 7062–7069 (1998).
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Shin, YK. K+ channel gating mechanism proposed using EPR. Nat Struct Mol Biol 5, 418–420 (1998). https://doi.org/10.1038/nsb0698-418
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DOI: https://doi.org/10.1038/nsb0698-418