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New tricks from an itinerant intron

A new mechanism for transposition by autocatalytic group II introns provides a working model for intron dispersal in eukaryotic genomes.

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Figure 1: Splicing of group II introns is a reversible, two-step process.
Figure 2: Two pathways for retrotransposition of group II introns in Lactococcus lactis:

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Acknowledgements

I wish to thank Q. Xiang, T. Bestor and P. Pang for their helpful comments on this manuscript and N. Craig for information on transposon abundance.

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Pyle, A. New tricks from an itinerant intron. Nat Struct Mol Biol 7, 352–354 (2000). https://doi.org/10.1038/75111

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