Three-dimensional structures for the INK4 proteins should reveal how the plethora of p16INK4a mutations found in human tumors might alter its function as a cyclin-dependent kinase inhibitor.
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McDonald, N., Peters, G. Ankyrin for clues about the function 0fp16INK4a. Nat Struct Mol Biol 5, 85–88 (1998). https://doi.org/10.1038/nsb0298-85
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DOI: https://doi.org/10.1038/nsb0298-85