A new, inherently flexible, predominantly α-helical RNA binding motif has been detected in two rather conserved ribosomal proteins. Comparative studies prompt the suggestion that these ribosomal proteins are the ancestors of this new helix-turn-helix fold, also found in homeodomains.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Liljas, A. & Garber, M. Curr. Op. Struct. Biol. 5, 721–727 (1995).
Nikonov, S. et al. EMBO J. 15, 1350–1359 (1996).
Davies, C., Ramakrishnan, V. & White, S.W. Structure 4, 1093–1104 (1996).
Berglund, H. et al. Nature Struct. Biol. 4, 20–23 (1996).
Markus, M.A. et al. Nature Struct. Biol. 4, 70–76 (1996).
Xing, Y., Takurta, D.G. & Draper, D.E. Nature Struct. Biol. 4, 24–27 (1996).
von Bohlen, K. et al. J. Mol. Biol. 222, 11–15 (1991).
Schluenzen, F. et al. J. Biochem. Cell Biol. 73, 739–749 (1995).
Cusack, S. et al. Nature 347, 249–255 (1990).
Goldgur, Y. et al. Structure in the press.
Nomura, M., Course, R. & Baughman, G. Ann. Rev. Biochem. 53, 75–117 (1984).
Evers, U., Franceschi, F., Boeddeker, N. & Yonath, A. Bioph. Chem. 50, 3–9 (1994).
Ye, X., Gorin, A., Ellington, A.D. & Patel, D.J. Nature Struct. Biol. 3, 1026–1033 (1996).
Batiste, T.L. Science 273, 1547–1551 (1996).
Mosyak, L. et al. Nature Struct. Biol. 2, 537–547 (1995).
Cusak, S. Biochimi 75, 1077–1081 (1993).
Weinstein, S., Jahn, W., Wittmann, H.G. & Yonath, A. J. Biol. Chem. 264, 19138–19142 (1989).
Bartels, H. et al. J. Peptide Sciences 37, 411–419 (1995).
Xing, Y. & Draper, D.E. Biochemistry 35, 1581–88 (1996).
Sagi, I. et al. Biophys. Chem. 55, 31–41 (1955).
Heinrich, T., Erdmann, V.A. & Hartmann, R.K. Gene, 136, 373–374 (1993).
Choli, T. Biochem. Intern. 19, 1323–1338 (1989).
Thygesen, J., Weinstein, S., Franceschi, F. & Yonath, A. Structure 4, 513–518 (1996).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Yonath, A., Franceschi, F. New RNA recognition features revealed in ancient ribosomal proteins. Nat Struct Mol Biol 4, 3–5 (1997). https://doi.org/10.1038/nsb0197-3
Issue Date:
DOI: https://doi.org/10.1038/nsb0197-3
This article is cited by
-
Structural aspects of protein synthesis
Nature Structural Biology (1997)
-
Antibiotics and RNA
Nature Structural Biology (1997)
