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Prostate cancer

Clinical implications of therapeutic sequence in mCRPC

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In the field of advanced prostate cancer, a number of therapeutic agents are now available. The sequence of administration of medications with distinct mechanisms of action, toxicities and efficacies, will have a critical role in disease outcomes. The identification of biomarkers predicting response will help to determine the appropriate therapeutic sequence.

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Correspondence to Ulka Vaishampayan.

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Competing interests

U.V. is a speaker for Bayer, Janssen and Astellas/Medivation, a consultant for Astellas/Medivation, and has research support from Astellas/Medivation.

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Vaishampayan, U. Clinical implications of therapeutic sequence in mCRPC. Nat Rev Urol 12, 13–14 (2015). https://doi.org/10.1038/nrurol.2014.308

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