A new nomogram to predict minimal prostate cancer (tumors of less than 0.5 cm3, organ-confined disease and no Gleason pattern 4 or 5) has been developed. O'Brien et al. used preoperative data from 2,525 Australian men, and compared accuracy and error rates to the contemporary Epstein criteria and the Prostate Cancer Research International: Active Surveillance trial inclusion criteria. 152 men had minimal cancer at prostatectomy and the predictive accuracy of the nomogram was 93.3%, compared to 89.1% and 91.0% for the Epstein criteria and the Prostate Cancer Research International: Active Surveillance trial inclusion criteria, respectively.
ORIGINAL RESEARCH PAPER
O'Brien, B. A. et al. A new preoperative nomogram to predict minimal prostate cancer: accuracy and error rates compared to other tools to select patients for active surveillance. J. Urol. 186, 1811–1817 (2011)
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New preoperative nomogram predicts minimal disease. Nat Rev Urol 8, 650 (2011). https://doi.org/10.1038/nrurol.2011.188
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DOI: https://doi.org/10.1038/nrurol.2011.188