A new nomogram to predict minimal prostate cancer (tumors of less than 0.5 cm3, organ-confined disease and no Gleason pattern 4 or 5) has been developed. O'Brien et al. used preoperative data from 2,525 Australian men, and compared accuracy and error rates to the contemporary Epstein criteria and the Prostate Cancer Research International: Active Surveillance trial inclusion criteria. 152 men had minimal cancer at prostatectomy and the predictive accuracy of the nomogram was 93.3%, compared to 89.1% and 91.0% for the Epstein criteria and the Prostate Cancer Research International: Active Surveillance trial inclusion criteria, respectively.