Tyrosine kinase inhibitors delay tumor progression and have a favorable adverse effect profile in patients with metastatic renal cell carcinoma; however, the impact of these treatments on objective clinical outcomes remains unknown. Updated results from two landmark phase III randomized trials now demonstrate the effect of sunitinib and sorafenib on survival.
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New insights into long noncoding RNAs and pseudogenes in prognosis of renal cell carcinoma
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Breau, R., Leibovich, B. Therapy for metastatic RCC—questions remain. Nat Rev Urol 6, 580–581 (2009). https://doi.org/10.1038/nrurol.2009.210
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DOI: https://doi.org/10.1038/nrurol.2009.210
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New insights into long noncoding RNAs and pseudogenes in prognosis of renal cell carcinoma
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