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Epilepsy

Should valproate be avoided during childbearing years?

Nature Reviews Neurology volume 5, pages 414–415 (2009)Cite this article

In utero exposure to antiepileptic drugs carries teratogenic risks, but little is known about the potential effects of such agents on neurocognitive development. The results from a large prospective study that set out to address this issue add to the mounting evidence against the use of valproate in women with epilepsy during childbearing years.

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Authors and Affiliations

  1. Department of Neurology, University of California San Francisco, San Francisco, USA

    Luigi Maccotta & Joseph E. Sullivan

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  1. Luigi Maccotta
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  2. Joseph E. Sullivan
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Correspondence to Joseph E. Sullivan.

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The authors declare no competing financial interests.

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Maccotta, L., Sullivan, J. Should valproate be avoided during childbearing years?. Nat Rev Neurol 5, 414–415 (2009). https://doi.org/10.1038/nrneurol.2009.92

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