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Acute kidney injury in 2010

Advances in diagnosis and estimating disease prognosis

Acute kidney injury (AKI) is a serious complication associated with morbidity and mortality. Studies from 2010 have provided insights into the diagnosis and clinical course of AKI, the ability of novel biomarkers to guide therapy, and the quality of life of survivors of severe AKI. It is hoped that these findings will lead to improvements in the diagnosis and prognosis of affected individuals.

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References

  1. Uchino, S. et al. Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 294, 813–818 (2005).

    Article  CAS  Google Scholar 

  2. Lo, L. J. et al. Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease. Kidney Int. 76, 893–899 (2009).

    Article  CAS  Google Scholar 

  3. Bouchard, J. et al. Fluid accumulation, survival and recovery of kidney function in critically ill patients with acute kidney injury. Kidney Int. 76, 422–427 (2009).

    Article  Google Scholar 

  4. Macedo, E. et al. Fluid accumulation, recognition and staging of acute kidney injury in critically-ill patients. Crit. Care 14, R82 (2010).

    Article  Google Scholar 

  5. Perazella, M. A. et al. Urine microscopy Is associated with severity and worsening of acute kidney injury in hospitalized patients. Clin. J. Am. Soc. Nephrol. doi:10.2215/CJN.06960909.

    Article  Google Scholar 

  6. Darmon, M. et al. Diagnostic accuracy of Doppler renal resistive index for reversibility of acute kidney injury in critically ill patients. Intensive Care Med. doi:10.1007/s00134-010-2050-y.

    Article  Google Scholar 

  7. Endre, Z. H. et al. Early intervention with erythropoietin does not affect the outcome of acute kidney injury (the EARLYARF trial). Kidney Int. 77, 1020–1030 (2010).

    Article  CAS  Google Scholar 

  8. Gordon, A. C. et al. The effects of vasopressin on acute kidney injury in septic shock. Intensive Care Med. 36, 83–91 (2010).

    Article  CAS  Google Scholar 

  9. Lafrance, J. P. & Miller, D. R. Acute kidney injury associates with increased long-term mortality. J. Am. Soc. Nephrol. 21, 345–352 (2010).

    Article  Google Scholar 

  10. Johansen, K. L. et al. Predictors of health utility among 60-day survivors of acute kidney injury in the Veterans Affairs/National Institutes of Health Acute Renal Failure Trial Network Study. Clin. J. Am. Soc. Nephrol. 5, 1366–1372 (2010).

    Article  Google Scholar 

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Correspondence to Sean M. Bagshaw.

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Competing interests

S. M. Bagshaw has received consulting/speaking fees from Alere and from Gambro Renal Products. R. Wald declares no competing interests.

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Bagshaw, S., Wald, R. Advances in diagnosis and estimating disease prognosis. Nat Rev Nephrol 7, 70–71 (2011). https://doi.org/10.1038/nrneph.2010.185

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