Haller et al. demonstrated that irinotecan plus oxaliplatin (IROX) is more efficacious than irinotecan alone after fluoropyrimidine failure in advanced colorectal cancer. IROX does not change, but enriches the treatment algorithm of advanced colorectal cancer at the second-line level.
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Supported by the Associazione Italiana per la Ricerca sul Cancro.
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A. Sobrero is a Consultant and on the Speakers bureau for the following companies: Roche, Merck KGA, Amgen and Sanofi-Aventis.
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Sobrero, A. IROX as second-line therapy for metastatic colorectal cancer. Nat Rev Clin Oncol 6, 248–250 (2009). https://doi.org/10.1038/nrclinonc.2009.43
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DOI: https://doi.org/10.1038/nrclinonc.2009.43
