First-line platinum and taxane chemotherapy improves the prognosis of patients with epithelial ovarian cancer (EOC), however, about 80% of patients relapse and long-term survival is poor. The development of drug resistance is the main cause of treatment failure; therefore, the identification of new compounds that interfere with tumor growth and survival is a priority.
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Sessa, C., Del Conte, G. Tailored treatment for ovarian cancer: are we there yet?. Nat Rev Clin Oncol 7, 80–82 (2010). https://doi.org/10.1038/nrclinonc.2009.233
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DOI: https://doi.org/10.1038/nrclinonc.2009.233