Abstract
MicroRNAs (miRNAs) are known to translationally repress or post-transcriptionally regulate mRNAs and are responsible for many diseases. We are preparing a comprehensive framework of co-expression analysis to figure out co-expression, differential co-expression and co-expression dynamics within multiple phenotypes in expression profiles. The purpose is to elucidate the disease association of miRNAs via co-regulatory pattern analysis.
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Bhattacharyya, M. Mining Co-expression Graphs: Applications to MicroRNA Regulation and Disease Analysis. Nat Prec (2012). https://doi.org/10.1038/npre.2012.7119.1
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DOI: https://doi.org/10.1038/npre.2012.7119.1