The use of fluorescent tagging and nanoscale waveguides looks set to make real-time DNA sequencing a realistic proposition. Commercial devices based on nanophotonics are expected in 2010.
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Pile, D. Eavesdropping on DNA replication. Nature Photon 3, 79–80 (2009). https://doi.org/10.1038/nphoton.2008.283
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DOI: https://doi.org/10.1038/nphoton.2008.283