Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Mechanochemistry

Force probes in a bottle

A rigid molecule that changes shape when exposed to light can be used to explore the influence of mechanical force on chemical reactions involving small functional groups.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Molecular force probes are synthesized by forming a relatively unstrained ring that is then photochemically switched into a highly strained state.

References

  1. Neuman, K. C. & Nagy, A. Nature Methods 5, 491–505 (2008).

    Article  CAS  Google Scholar 

  2. Yang, Q.-Z. et al. Nature Nanotech. 4, 302–306 (2009).

    Article  CAS  Google Scholar 

  3. Hohng, S. et al. Science 318, 279–283 (2007).

    Article  CAS  Google Scholar 

  4. Huang, Z. et al. J. Am. Chem. Soc. 131, 1407–1409 (2009).

    Article  CAS  Google Scholar 

  5. Hickenboth, C. R. et al. Nature 446, 423–427 (2007).

    Article  CAS  Google Scholar 

  6. Wiita, A. P. et al. Nature 450, 124–127 (2007).

    Article  CAS  Google Scholar 

  7. Kersey, F. R., Yount, W. C. & Craig, S. L. J. Am. Chem. Soc. 128, 3886–3887 (2006).

    Article  CAS  Google Scholar 

  8. Schmidt, S. W., Beyer, M. K. & Clausen-Schaumann, H. J. Am. Chem. Soc. 130, 3664–3668 (2008).

    Article  CAS  Google Scholar 

  9. Sheiko, S. S. et al. Nature 440, 191–194 (2006).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lenhardt, J., Craig, S. Force probes in a bottle. Nature Nanotech 4, 284–285 (2009). https://doi.org/10.1038/nnano.2009.100

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nnano.2009.100

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing