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Nanomedicine

Seeing the benefits of ceria

Nature Nanotechnology volume 1, pages 92–94 (2006)Cite this article

Cerium oxide nanoparticles can scavenge reactive molecules in the eye and prevent degenerative retinal disorders in rats. The results suggest that nanoceria particles could be used to treat a variety of problems that cause blindness.

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Figure 1
Figure 2: a, By switching between the +3 and +4 valence states (top), nanoceria particles can reversibly scavenge free electrons from the reactive oxygen species (OH• and O2•−), to produce less harmful molecules (OH− and O2).

References

  1. Klein, R., Klein, B. E. & Linton, K. L. Ophthalmology 99, 933–943 (1992).

    Article  CAS  Google Scholar 

  2. Augood, C. A. et al. Arch. Ophthalmol. 124, 529–35 (2006).

    Article  Google Scholar 

  3. Sanvicens, N. et al. J. Biol. Chem. 279, 39268–78 (2004).

    Article  CAS  Google Scholar 

  4. Chang, G. Q., Hao, Y. & Wong, F. Neuron 11, 595–605 (1993).

    Article  CAS  Google Scholar 

  5. Chen, J., Patil, S., Seal, S. & McGinnis, J. F. Nature Nanotech. 1, 142–150 (2006).

    Article  CAS  Google Scholar 

  6. Braun, R. D., Linsenmeier, R. A. & Goldstick, T. K. Invest. Ophthalmol. Vis. Sci. 36, 542–54 (1995).

    CAS  Google Scholar 

  7. Deshpande, S., Swanand Patil, S., Kuchibhatla, S. & Seal, S. Appl. Phys. Lett. 87, 133113 (2005).

    Article  Google Scholar 

  8. Pepperberg, D. R. Prog. Brain Res. 131, 369–81 (2001).

    Article  CAS  Google Scholar 

Download references

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  1. Departments of Bioengineering and Ophthalmology, University of California, San Diego, La Jolla, 92037-0946, California, USA

    Gabriel A. Silva

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  1. Gabriel A. Silva
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Silva, G. Seeing the benefits of ceria. Nature Nanotech 1, 92–94 (2006). https://doi.org/10.1038/nnano.2006.111

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