Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Exciting guts with GABA

Nature Neuroscience volume 6, pages 1121–1122 (2003)Cite this article

A new study in this issue demonstrates that two GABAergic motor neurons in C. elegans are excitatory at target muscles because GABA activates a ligand-gated cation conductance, which is structurally similar to several other ligand-gated channels.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Mechanisms underlying the excitatory and inhibitory actions of GABA in C. elegans and in vertebrates.

References

  1. Beg, A.A. & Jorgensen, E.M. Nat. Neurosci, 6, 1145–1152 (2003).

    Article  CAS  Google Scholar 

  2. Gutovitz, S., Birmingham, J.T., Luther, J.A., Simon, D.J. & Marder, E. J. Neurosci. 21, 5935–5943 (2001).

    Article  CAS  Google Scholar 

  3. Swensen, A.M. et al. J. Exp. Biol. 203, 2075–2092 (2000).

    CAS  PubMed  Google Scholar 

  4. Norekian, T.P. J. Neurosci. 19, 1863–1875 (1999).

    Article  CAS  Google Scholar 

  5. Yarowsky, P.J. & Carpenter, D.O. Brain Res. 144, 75–94 (1978).

    Article  CAS  Google Scholar 

  6. Kehoe, J. & Vulfius, C. J. Neurosci. 20, 8585–8596 (2000).

    Article  CAS  Google Scholar 

  7. Kehoe, J. J. Physiol. (Lond.) 225, 115–146 (1972).

    Article  CAS  Google Scholar 

  8. Lingle, C. & Marder, E. Brain Res. 212, 481–488 (1981).

    Article  CAS  Google Scholar 

  9. McIntire, S.L., Jorgensen, E. & Horvitz, H.R. Nature 364, 334–337 (1993).

    Article  CAS  Google Scholar 

  10. McIntire, S.L., Jorgensen, E., Kaplan, J. & Horvitz, H.R. Nature 364, 337–341 (1993).

    Article  CAS  Google Scholar 

  11. Thomas, J.H. Genetics 124, 855–872 (1990).

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Bamber, B.A., Beg, A.A., Twyman, R.E. & Jorgensen, E.M. J. Neurosci. 19, 5348–5359 (1999).

    Article  CAS  Google Scholar 

  13. Moorhouse, A.J., Keramidas, A., Zaykin, A., Schofield, P.R. & Barry, P.H. J. Gen. Physiol. 119, 411–425 (2002).

    Article  CAS  Google Scholar 

  14. Ben-Ari, Y. Trends Neurosci. 24, 353–360 (2001).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Volen Center, Brandeis University, Waltham, 02454–9110, MA, USA

    Jean-Marc Goaillard & Eve Marder

Authors
  1. Jean-Marc Goaillard
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Eve Marder
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Goaillard, JM., Marder, E. Exciting guts with GABA. Nat Neurosci 6, 1121–1122 (2003). https://doi.org/10.1038/nn1103-1121

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nn1103-1121

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing