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A new form of feedback at the GABAA receptor

Nature Neuroscience volume 4, pages 674–676 (2001)Cite this article

GABA is inhibitory in adults, but it is excitatory in young animals. A recent study shows that activation of the GABAA receptor itself may promote this developmental switch.

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Figure 1: A little chloride goes a long way.

Amy Center

Figure 2: GABAA receptor activation is the newest link in the chain of events that change the effect of GABAA receptor activation from excitation to inhibition.

Bob Crimi

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Authors and Affiliations

  1. University of Colorado Health Sciences Center, Box B182, 4200 East 9th Avenue, Denver, 80262, Colorado, USA

    Kevin Staley & Roderic Smith

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  1. Kevin Staley
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  2. Roderic Smith
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Staley, K., Smith, R. A new form of feedback at the GABAA receptor. Nat Neurosci 4, 674–676 (2001). https://doi.org/10.1038/89439

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