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Shaking up sleep research

Nature Neuroscience volume 8, pages 703–705 (2005)Cite this article

Sleep deprivation causes all too familiar behavioral impairments and increased need for sleep. A new Drosophila mutant with alterations in the Shaker potassium channel sleeps less than normal but does not show the usual effects of sleep deprivation.

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Figure 1: Shaker channel minisleep mutant flies have altered responses to sleep deprivation.

Ivelisse Robles

Figure 2: Multiple model systems facilitate effective studies.

Ann Thomson

References

  1. Cirelli, C. et al. Nature 434, 1087–1092 (2005).

    Article  CAS  Google Scholar 

  2. Espinosa, F., Marks, G., Heintz, N. & Joho, R.H. Genes Brain Behav. 3, 90–100 (2004).

    Article  CAS  Google Scholar 

  3. Josephs, K.A. et al. J. Clin. Neurophysiol. 21, 440–445 (2004).

    Article  Google Scholar 

  4. Hendricks, J.C. et al. Neuron 25, 129–138 (2000).

    Article  CAS  Google Scholar 

  5. Shaw, P.J., Cirelli, C., Greenspan, R.J. & Tononi, G. Science 287, 1834–1837 (2000).

    Article  CAS  Google Scholar 

  6. Kilduff, T.S. Neuron 26, 295–298 (2000).

    Article  CAS  Google Scholar 

  7. Hendricks, J.C. et al. Nat. Neurosci. 4, 1108–1115 (2001).

    Article  CAS  Google Scholar 

  8. Graves, L. et al. J. Neurophysiol. 90, 1152–1159 (2003).

    Article  CAS  Google Scholar 

  9. Hendricks, J.C. et al. J. Biol. Rhythms 18, 12–25 (2003).

    Article  CAS  Google Scholar 

  10. Shaw, P.J., Tononi, G., Greenspan, R.J. & Robinson, D.F. Nature 417, 287–291 (2002).

    Article  CAS  Google Scholar 

  11. Hendricks, J.C., Kirk, D., Panckeri, K., Miller, M.S. & Pack, A.I. Sleep 26, 139–146 (2003).

    Article  Google Scholar 

  12. Benington, J.H. & Heller, H.C. Prog. Neurobiol. 45, 347–360 (1995).

    Article  CAS  Google Scholar 

  13. Espinosa, F., Marks, G., Heintz, N. & Joho, R.H. Genes Brain Behav. 3, 90–100 (2004).

    Article  CAS  Google Scholar 

  14. Horne, J.A. & McGrath, M.J. Biol. Psychol. 18, 165–184 (1984).

    Article  CAS  Google Scholar 

  15. O'Brien, L.M. & Gozal, D. Minerva Pediatr. 56, 585–601 (2004).

    CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Clinical Studies, Philadelphia School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Joan C Hendricks

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  1. Joan C Hendricks
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Hendricks, J. Shaking up sleep research. Nat Neurosci 8, 703–705 (2005). https://doi.org/10.1038/nn0605-703

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