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Sighs and gasps in a dish

The isolated vertebrate brainstem can produce not only the normal breathing rhythm, but also sighs and gasps. All three patterns may involve the same neural circuit.

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Figure 1: (a) Respiratory-like rhythmic behavior can be recorded from the preBötzinger complex in a transverse slice (250–800 μm thick) of the brainstem of late fetal, neonatal and juvenile rats.

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Feldman, J., Gray, P. Sighs and gasps in a dish. Nat Neurosci 3, 531–532 (2000). https://doi.org/10.1038/75695

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