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How do dendrites take their shape?

Nature Neuroscience volume 4, pages 359–365 (2001)Cite this article

Abstract

Recent technical advances have made possible the visualization and genetic manipulation of individual dendritic trees. These studies have led to the identification and characterization of molecules that are important for different aspects of dendritic development. Although much remains to be learned, the existing knowledge has allowed us to take initial steps toward a comprehensive understanding of how complex dendritic trees are built. In this review, we describe recent advances in our understanding of the molecular mechanisms underlying dendritic morphogenesis, and discuss their cell-biological implications.

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Figure 1: Visualizing individual dendrites.
Figure 2: Major steps of dendritic development.

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Acknowledgements

We thank Y.-N. Jan, S. Smith, A. Goldstein and J. Ng for their comments on this review. Work in our lab is supported by grants from the NIH.

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  1. Department of Biological Sciences, Stanford University, Stanford, 94305, California, USA

    Ethan K. Scott & Liqun Luo

  2. Neurosciences Program, Stanford University, Stanford, 94305, California, USA

    Liqun Luo

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Correspondence to Liqun Luo.

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Scott, E., Luo, L. How do dendrites take their shape?. Nat Neurosci 4, 359–365 (2001). https://doi.org/10.1038/86006

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