A fluorescence resonance energy transfer (FRET)-based biosensor helps scientists monitor the activation of an essential signaling protein over the course of embryogenesis in Drosophila melanogaster.
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References
Kamiyama, D. & Chiba, A. Endogenous activation patterns of Cdc42 GTPase within Drosophila embryos. Science 324, 1338–1340 (2009).
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Eisenstein, M. Actions speak louder. Nat Methods 6, 556–557 (2009). https://doi.org/10.1038/nmeth0809-556a
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DOI: https://doi.org/10.1038/nmeth0809-556a