By adding new connections between unrelated genes to a gene network, researchers can investigate network robustness and evolvability.
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References
Isalan, M. et al. Evolvability and hierarchy in rewired bacterial gene networks. Nature 452, 840–845 (2008).
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Doerr, A. Rewiring E. coli. Nat Methods 5, 464–465 (2008). https://doi.org/10.1038/nmeth0608-464b
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DOI: https://doi.org/10.1038/nmeth0608-464b