Understanding of the sequelae of cerebral microvascular injury has been hampered by a lack of animal models to enable precise localization of injury. In this issue, Nishimura et al. describe a stroke model that couples two-photon laser-scanning mapping of the cerebral cortex with femtosecond laser technology to produce three distinct microvascular injuries characterized by hemorrhage, vessel leakage or vessel occlusion.
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Katie Ris
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Flaumenhaft, R., Lo, E. Different strokes for rodent folks. Nat Methods 3, 79–80 (2006). https://doi.org/10.1038/nmeth0206-79
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DOI: https://doi.org/10.1038/nmeth0206-79
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