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Drug delivery

Stealth particles give mucus the slip

Nature Materials volume 8, pages 11–13 (2009)Cite this article

Mucus presents a formidable barrier to nanoparticle drug-delivery systems, but adding a coating of polymer molecules helps them sneak through the net.

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Figure 1: Mucus structure and its role in drug delivery.
Figure 2: A scaled representation of the mucus gel depicted as a complex, porous network, and some relevant foreign constituents.

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Authors and Affiliations

  1. Yen Cu and W. Mark Saltzman are in the Department of Biomedical Engineering, Yale University, PO Box 208284, New Haven, Connecticut 06520-8284, USA. mark.saltzman@yale.edu,

    Yen Cu & W. Mark Saltzman

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  1. Yen Cu
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  2. W. Mark Saltzman
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Cu, Y., Saltzman, W. Stealth particles give mucus the slip. Nature Mater 8, 11–13 (2009). https://doi.org/10.1038/nmat2347

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