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Cellular matrices

Physiology in microfluidics

Nature Materials volume 7, pages 609–610 (2008)Cite this article

The in vivo characteristics of the extracellular matrix, such as biochemical, mechanical and flow properties, are a challenge to mimic in vitro. Now, a three-dimensional hydrogel structure with integrated multiple phases shows promise as such a model.

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Figure 1: Templated growth of collagen fibrils within a microfluidic device.
Figure 2: Biochemical and biophysical influences on a cell (blue).

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Authors and Affiliations

  1. Jeffrey A. Hubbell is in the Institutes of Bioengineering and Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland. jeffrey.hubbell@epfl.ch,

    Jeffrey A. Hubbell

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  1. Jeffrey A. Hubbell
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Hubbell, J. Physiology in microfluidics. Nature Mater 7, 609–610 (2008). https://doi.org/10.1038/nmat2238

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