Cancer can ensue when cells do not know who they are or where they are. In the intestine, a single regulator seems to take care of both of these issues of identity.
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Booth, C., Brady, G. & Potten, C. Crowd control in the crypt. Nat Med 8, 1360–1361 (2002). https://doi.org/10.1038/nm1202-1360
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DOI: https://doi.org/10.1038/nm1202-1360
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