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Immune alteration fends off AIDS

Comparative studies of the immune response to simian immunodeficiency virus in two nonhuman primate species provide insight into a central aspect of HIV infection—the ability of the virus to cause chronic activation of the immune system (pages 1077–1087).

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Figure 1: Differential expression of IFN-α by sooty mangabeys and rhesus macaques in SIV infection.

Kim Caesar

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O'Connell, K., Siliciano, R. Immune alteration fends off AIDS. Nat Med 14, 1016–1018 (2008). https://doi.org/10.1038/nm1008-1016

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