Kaposi sarcoma-associated herpesvirus (KSHV) is linked to the development of Kaposi sarcoma and certain lymphoproliferative malignancies. The main immunogenic latent nuclear antigen of KSHV can form a complex with retinoblastoma tumor suppressor protein and transform cells, indicating that the oncogenic activities of KSHV are mechanistically related to the transforming functions of the small DNA tumor viruses (pages 1121–1127).
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Münger, K. Learning old tricks from new viruses. Nat Med 6, 1091–1092 (2000). https://doi.org/10.1038/80409
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DOI: https://doi.org/10.1038/80409