Abstract
Two new mouse studies suggest that PPARγ agonists may promote tumorigenesis in colon epithelium whereas a third study in humans indicates a possible protective role for these drugs (pages 1046–1061).
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Acknowledgements
I thank R. Xavier and J. Avruch for helpful comments and B. Spiegelman for the communication of unpublished results.
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Seed, B. PPARγ and colorectal carcinoma: Conflicts in a nuclear family. Nat Med 4, 1004–1005 (1998). https://doi.org/10.1038/1990
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DOI: https://doi.org/10.1038/1990
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