Bone marrow–derived stem cells have been used with some success in animal models to repair ischemic damage to the heart. Overexpression of the survival-promoting signal Akt greatly enhances the ability of these cells to heal a heart after myocardial infarction (pages 1195–1201).
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Koç, O., Gerson, S. Akt helps stem cells heal the heart. Nat Med 9, 1109–1110 (2003). https://doi.org/10.1038/nm0903-1109
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DOI: https://doi.org/10.1038/nm0903-1109
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