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Akt helps stem cells heal the heart

Bone marrow–derived stem cells have been used with some success in animal models to repair ischemic damage to the heart. Overexpression of the survival-promoting signal Akt greatly enhances the ability of these cells to heal a heart after myocardial infarction (pages 1195–1201).

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Figure 1: Surviving in a hostile heart.

Renee Lucas

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Koç, O., Gerson, S. Akt helps stem cells heal the heart. Nat Med 9, 1109–1110 (2003). https://doi.org/10.1038/nm0903-1109

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