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Neural stem cells—Where are you?

One of the mysteries about stem cells in the adult brain is where they arise during development. A recent study of human neural stem cells transplanted into monkey embryos provides insight into the derivation of these cells in the primate embryo.

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Figure 1: Cells are injected into the forebrain ventricle of a monkey embryo, during an early phase of development (left) when precursor cells of the VZ are generating endogenous cortical neurons.

Stephen Horwitz

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Price, J. Neural stem cells—Where are you?. Nat Med 7, 998–999 (2001). https://doi.org/10.1038/nm0901-998

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