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References
Moghaddam, M.F. et al Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase. Nat. Med. 3, 336 (1997).
Ishizaki, T., Takahashi, H., Ozawa, S.-W. & Voelkel, N.F. Leukotoxin, 9,10-epoxy-12-octadecenoate causes pulmonary vasodilation in rats. Am. J. Physiol. 268 123–128 (1995).
Ishizaki, T. et al. Increased nitric oxide biosynthesis in leukotoxin, 9, 10-epoxy-12-octadecenoate injured lung. Biochem. Biophys. Res. Commun. 210, 133–137 (1995).
Ishizaki, T. et al. Leukotoxin, 9, 10-epoxy-12-octadecenoate causes edematous lung injury via activation of vascular nitric oxide synthase. Am. J. Physiol. 269, 65–70 (1995).
Sakai, T. et al. Role of nitric oxide and superoxide anion in leukotoxin, 9, 10-epoxy-12-octadecenoate-induced mitochondrial dysfunction. Free Rod. Biol. & Med. 20 607–612 (1996).
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Hammock, B. Are leukotoxins toxic?. Nat Med 3, 592 (1997). https://doi.org/10.1038/nm0697-592b
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DOI: https://doi.org/10.1038/nm0697-592b