It is widely anticipated that the sequencing of the human genome, the characterization of the human proteomic map and the underlying advance in technological know-how will give rise to an unprecedented leap in biomedical science over the next half century. It may be that the bottleneck in the equation is the availability of staff trained to understand the scientific data generated and transform it successfully into something with medical value. Such people must have detailed knowledge both of medicine and the practice of scientific investigation. Here, we present three commentaries that endeavor to explain how such hybrid researchers can be recruited, trained and retained.
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References
Rosenberg, L. Physician-scientists—endangered and essential. Science 283, 331–332 (1999).
Wyngaarden, J.B. The clinical investigator as an endangered species. N. Engl. J. Med. 301, 1254–1259 (1979).
Zemlo, T.R., Garrison, H.H., Partridge, N.C. & Ley, T.J. The physician-scientist: Career issues and challenges at the year 2000. FASEB J. 14, 221–230 (2000).
Varki, A. & Rosenberg, L.E. Emerging opportunities and career paths for the young physician-scientist. Nature Med. 8, 437–439 (2002).
Abelmann, W.H., Nave, B.D. & Wilkerson, L. Generation of physician-scientists manpower: A follow-up study of the first 294 graduates of the Harvard-MIT Program of Health Sciences and Technology. J. Invest. Med. 45, 272–275 (1997).
Wilkerson, L. & Abelmann, W.H. Producing physician-scientists: A survey of graduates from the Harvard-MIT Program in Health Sciences and Technology. Acad. Med. 68, 214–218 (1993).
Arias, I.M. Training basic scientists to bridge the gap between basic science and its application to human disease. N. Engl. J. Med. 321, 972–974 (1989).
Arias, I. Bridge building between medicine and basic science. Proc. Natl. Acad. Sci.: USA (in the press).
Bunn, H.F. & Casey, C.G. Educating the biomedical scientist. FASEB J. 9, 1392–1395 (1995).
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Gray, M., Bonventre, J. Training PhD researchers to translate science to clinical medicine: Closing the gap from the other side. Nat Med 8, 433–436 (2002). https://doi.org/10.1038/nm0502-433
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DOI: https://doi.org/10.1038/nm0502-433
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