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Thyroiditis and hepatitis: Fas on the road to disease

Nature Medicine volume 3, pages 387–388 (1997)Cite this article

Fas-mediated programmed cell death contributes to the pathology of thyroiditis and hepatitis (pages 409–413).

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References

  1. Nagata, S. Apoptosis by death factor. Cell 88, 355–365 (1992).

    Article  Google Scholar 

  2. Lenardo, M.J. Fas and the art of lymphocyte maintenance. J. Exp. Med. 183, 721–724 (1996).

    Article  CAS  Google Scholar 

  3. Kondo, T., Suda, T., Fukuyama, H., Adachi, M. & Nagata, S. Essential roles of the Fas ligand in the development of hepatitis. Nature Med. 3, 409–413 (1997).

    Article  CAS  Google Scholar 

  4. Giordano, C. et al. Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis. Science 275, 960–963 (1997).

    Article  CAS  Google Scholar 

  5. Galle, P.R. et al. Involvement of the CD95 (Apo-1/Fas) receptor and ligand in liver damage. J. Exp. Med. 182, 1223–1230 (1995).

    Article  CAS  Google Scholar 

  6. Chisari, F.V. & Ferrari, C. Hepatitis B virus immunopathogenesis. Annu. Rev. Immunol. 13, 29–60 (1995).

    Article  CAS  Google Scholar 

  7. Dayan, C.M. & Daniles, G.H. Chronic autoimmune thyroiditis. N. Engl. J. Med. 335, 99–107 (1996).

    Article  CAS  Google Scholar 

  8. Kotani, T. et al. Apoptosis in thyroid tissue from patients with Hashimoto's thyroiditis. Autoimmunity 20, 231–236 (1995).

    Article  CAS  Google Scholar 

  9. French, L.E. et al. Fas and Fas Ligand in embryos and adult mice: Ligand expression in several immune-privileged tissues and co-expression in adult tissues characterized by apoptotic Cell turnover. J. Cell Biol. 133, 335–343 (1996).

    Article  CAS  Google Scholar 

  10. Hahne, M. et al. Melanoma Cell expression of Fas (Apo1/CD95) ligand: Implications for tumor immune escape. Science 274, 1363–1366 (1996).

    Article  CAS  Google Scholar 

  11. Streilein, J.W. Unraveling immune privilege. Science 270, 1158–1159 (1995).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Dermatology Clinic, Geneva University Hospital, CH-1211, Geneva, 14

    Lars E. French

  2. Institut de Biochimie, Lausanne University, CH-1066, Epalinges, Switzerland

    Jürg Tschopp

Authors
  1. Lars E. French
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  2. Jürg Tschopp
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French, L., Tschopp, J. Thyroiditis and hepatitis: Fas on the road to disease. Nat Med 3, 387–388 (1997). https://doi.org/10.1038/nm0497-387

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