The search for an elusive association between MHC polymorphism and susceptibility to HIV and AIDS continues (pages 405–411).
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Kaslow, R.A. et al. Influence of combinations of major histocompatibility complex genes on the course of HIV infection. Nature Med. 2, 405–411 (1996).
Wei, X. et al. Viral dynamics in human immunodeficiency virus type 1 infections. Nature 373, 117–122 (1995).
Haynes, B.F., Pantaleo, G. & Fauci, A.S. Toward an understanding of the correlates of protective immunity to HIV infection. Science 271, 324–328 (1996).
Kroner, B.L. et al. Concordance of human leukocyte antigen haplotype-sharing, CD4 decline and AIDS in hemophilic siblings. AIDS 9, 275–280 (1995).
Scorza-Smeraldi, R. et al. HLA-associated susceptibility to acquired immunodeficiency syndrome in Italian patients with human-immunodeficiency-virus infection. Lancet 2, 1187–1189 (1986).
Steel, C.M. et al. HLA haplotype A1 B8 DR3 as a risk factor for HIV-related disease. Lancet 1, 1185–1188 (1988).
Cameron, P.U., Mallal, S.A., French, M.A. & Dawkins, R.L. Major histocompatibility complex genes influence the outcome of HIV infection: Ancestral haplotypes with C4 null alleles explain diverse HLA associations. Hum. Immunol. 29, 282–295 (1990).
McGuire, W., Hill, A.V.S., Allsopp, C.E., Greenwood, B.M. & Kwiatkowski, D. Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria. Nature 371, 508–510 (1994).
Kaslow, R.A. et al. A1, Cw7, B8, DR3 HLA antigen combination associated with rapid decline of T-helper lymphocytes in HIV-1 infection: A report from the Multicenter AIDS Cohort Study. Lancet 335, 927–930 (1990).
Davenport, M. & Hill, A.V.S. Reverse immunogenetics: From HLA-disease associations to vaccine candidates. Mol. Med. Today 2, 38–45 (1996).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hill, A. HIV and HLA: Confusion or complexity?. Nat Med 2, 395–396 (1996). https://doi.org/10.1038/nm0496-395
Issue Date:
DOI: https://doi.org/10.1038/nm0496-395
This article is cited by
-
Mannose-binding lectin haplotypes influence Brucella abortus infection in the water buffalo (Bubalus bubalis)
Immunogenetics (2008)
-
HLA-DQ6 and ingestion of contaminated water: possible gene–environment interaction in an outbreak of Leptospirosis
Genes & Immunity (2004)
-
Genetics of susceptibitlity to human infectious disease
Nature Reviews Genetics (2001)