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Cocaine's long run

Nature Medicine volume 10, pages 340–341 (2004)Cite this article

Locomotor activity in response to cocaine increases with repeated administration. A clever microarray approach now yields clues to the basis for this heightened sensitivity.

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Figure 1: The synaptic protein PSD-95 is a key regulator of locomotor responses to cocaine.

Courtesy of Tom Blanpied, Michael Ehlers

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Authors and Affiliations

  1. Department of Neuropharmacology, The Scripps Research Institute, La Jolla, 92037, California, USA

    Pietro Paolo Sanna & George F Koob

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  1. Pietro Paolo Sanna
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  2. George F Koob
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Sanna, P., Koob, G. Cocaine's long run. Nat Med 10, 340–341 (2004). https://doi.org/10.1038/nm0404-340

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