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Bad bones, grey hair, one mutation

Nature Medicine volume 9, pages 395–396 (2003)Cite this article

Osteopetrosis, a disease characterized by dense bones, is now pinned to the same gene that underlies a coat-color defect in mice (pages 399–406).

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Figure 1: Strange relationship? Chalhoub et al. identified a mutation in mice that affects both melanocytes and osteoclasts, and may cause osteopetrosis in humans.

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  1. University of Rochester Medical Center, Rochester, New York, USA

    Brendan F. Boyce

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  1. Brendan F. Boyce
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Boyce, B. Bad bones, grey hair, one mutation. Nat Med 9, 395–396 (2003). https://doi.org/10.1038/nm0403-395

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