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Fragile fugue: p53 in aging, cancer and IGF signaling

Nature Medicine volume 10, pages 231–232 (2004)Cite this article

Aging is driven in part by an evolutionarily conserved hormone signaling pathway. A new study shows that this pathway is controlled by the p53 tumor suppressor, which exquisitely balances the need for cell proliferation against that for tumor suppression.

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Figure 1: Short but mighty.

Renee Lucas

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Authors and Affiliations

  1. Buck Institute for Age Research and the Life Sciences Division at Lawrence Berkeley National Laboratory, Berkeley, 94720, California, USA

    Judith Campisi

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  1. Judith Campisi
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Campisi, J. Fragile fugue: p53 in aging, cancer and IGF signaling. Nat Med 10, 231–232 (2004). https://doi.org/10.1038/nm0304-231

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