Neuronal progenitor cells, isolated from the adult human dentate gyrus, are capable of proliferating and differentiating in vitro. Further studies into this approach may lead to neuronal transplantation therapies for human neurodegenerative disorders (271–277).
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
The proteome of neural stem cells from adult rat hippocampus
Proteome Science Open Access 12 June 2003
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Reddy, H. et al. Relating axonal injury to functional recovery in multiple sclerosis . Neurology 54, 236–239 (2000).
Roy, N.S. et al. In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus. Nature Med. 6, 271–277 (2000).
Vescovi, A.L. & Snyder, E.Y. Establishment and properties of neural stem cell clones: Plasticity in vitro and in vivo. Brain Pathol. 9, 569–598 (1999).
Eriksson, P. et al. Neurogenesis in the adult human hippocampus. Nature Med. 4, 1313–1317 ( 1998).
Kukekov, V. et al. Multipotent stem/progenitor cells with similiar properties arise from two neurogenic regions of the adult human brain. Exp. Neurol. 156, 333–44 ( 1999).
Pincus, D.W. et al. FGF2/BDNF-associated maturation of new neurons generated from adult human subependymal cells. Ann. Neurol. 43, 576–585 (1998).
Roy, N.S. et al. Identification, isolation, and promoter-defined separation of mitotic oligodendrocyte progenitor cells from the adult human subcortical white matter. J. Neurosci. 19, 9986– 9995 (1999).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Antel, J., Nalbantoglu, J. & Olivier, A. Neuronal progenitors—learning from the hippocampus. Nat Med 6, 249–250 (2000). https://doi.org/10.1038/73076
Issue Date:
DOI: https://doi.org/10.1038/73076
This article is cited by
-
The proteome of neural stem cells from adult rat hippocampus
Proteome Science (2003)