The disappearance of genetically modified CTLs following infusion into AIDS patients led to a surprising observation: What are the implications for active immunotherapy (pages 216–223)?
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Koenig, S. A lesson from the HIV patient: The immune response is still the bane (or promise) of gene therapy. Nat Med 2, 165–167 (1996). https://doi.org/10.1038/nm0296-165
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DOI: https://doi.org/10.1038/nm0296-165
