Sporadic breast cancers only rarely contain BRCA2 or BRCA1 mutations, despite the presence of such mutations in inherited breast and ovarian cancers. The identification of a new binding partner for BRCA-2 sheds light on this incongruity.
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Common variation in EMSYand risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs
BMC Cancer Open Access 19 July 2005
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Livingston, D. EMSY, a BRCA-2 partner in crime. Nat Med 10, 127–128 (2004). https://doi.org/10.1038/nm0204-127
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DOI: https://doi.org/10.1038/nm0204-127
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