A new study identifies the chemokine CCL27 and its receptor CCR10 as important homing molecules for T-cell migration to the skin. Moreover, they find that CCL27 inhibition suppresses some skin-inflammatory responses, suggesting that therapies targeting CCL10 could be used to treat several human skin disorders. (pages 157–165)
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Mackay, C. New avenues for anti-inflammatory therapy. Nat Med 8, 117–118 (2002). https://doi.org/10.1038/nm0202-117
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DOI: https://doi.org/10.1038/nm0202-117