Obesity-related chronic inflammation underlies insulin resistance, a key feature of type 2 diabetes. Recent data link the stress pathway of the endoplasmic reticulum to this phenomenon.
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de Luca, C., Olefsky, J. Stressed out about obesity and insulin resistance. Nat Med 12, 41–42 (2006). https://doi.org/10.1038/nm0106-41
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DOI: https://doi.org/10.1038/nm0106-41
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